Agent Skills
› brycewang-stanford/Awesome-Journal-Skills
› nejm-submission
nejm-submission
GitHubNEJM投稿前的最终预检技能，提供涵盖显著性、注册、报告规范、摘要、统计、图表、伦理及参考文献的完整临床检查清单。确保稿件符合期刊要求并防止退回修订中的遗漏。
Trigger Scenarios
稿件完成准备上传前
需确认其他neym-*技能输出已就位时
修订后防止问题复发时
Install
npx skills add brycewang-stanford/Awesome-Journal-Skills --skill nejm-submission -g -y
SKILL.md
Frontmatter
{
"name": "nejm-submission",
"description": "Use as the final preflight before submitting to NEJM — a complete clinical checklist across significance, registration, reporting guidelines, abstract, statistics, display items, ethics, references, and required files. Bundles a checklist and a clinical cover-letter template."
}
Submission Preflight (nejm-submission)
When to trigger
- The manuscript is "done" and you're about to upload.
- You want a single gate that confirms every other nejm-* skill's output landed.
- A revision is going back and you need to confirm nothing regressed.
Master preflight checklist
Significance & venue
- Clears the practice-changing / clinical-impact bar (
nejm-fitrung ≥ 4; all three gates). - Patient-important primary outcome (not surrogate-only).
- Article type chosen (Original Article / Brief Report) and within its length/reference caps.
Registration, protocol & SAP
- Trial prospectively registered (ClinicalTrials.gov / WHO ICTRP) before enrollment; registration number in hand.
- Registered primary outcome matches the reported primary outcome.
- Protocol and statistical analysis plan finalized, dated, and ready as a supplement.
Reporting guidelines
- Correct EQUATOR guideline (CONSORT / STROBE / PRISMA, + any extension) with completed checklist.
- CONSORT participant flow diagram (RCT) / PRISMA selection diagram (SR-MA) present.
- Flow-diagram numbers reconcile with Table 1 and the analysis populations.
Abstract
- Structured, four sections (Background / Methods / Results / Conclusions), ≤250 words.
- Primary outcome with effect estimate + 95% CI; ITT and per-group n stated.
- Registration number and funding source in the abstract.
Statistics
- CIs reported with effect estimates (not P alone); exact P values.
- ITT primary analysis; per-protocol as sensitivity (both for non-inferiority).
- Multiplicity controlled; exploratory endpoints labeled.
- Subgroups pre-specified with interaction tests (forest plot).
- Absolute risk + NNT alongside relative measures; missing-data handling stated.
Display items
- Table 1 by group, no baseline P values (standardized differences if used).
- Kaplan–Meier with numbers-at-risk; forest plots for subgroups/meta.
- Figures de-identified; CIs shown; colorblind-safe; standalone legends.
Ethics & integrity
- IRB/ethics approval + informed consent stated; Declaration of Helsinki / GCP.
- ICMJE disclosure forms for all authors; competing-interests statement.
- ICMJE authorship criteria met; contributors acknowledged; medical writers disclosed.
- Role-of-the-funding-source statement; data access/vouching for sponsored trials.
- Data-sharing statement (ICMJE) — what / when / to whom / how.
References
- Vancouver / ICMJE numbered style, ordered by appearance.
- First six authors then et al.; NLM journal abbreviations; within reference cap.
- All in-text superscript numbers resolve; no gaps/duplicates.
Required files & metadata
- Main text (title page, structured abstract, IMRAD, references).
- Figures + legends; tables (incl. Table 1) and the CONSORT flow diagram.
- Supplementary appendix: protocol + SAP, supp tables/figures.
- Cover letter (clinical importance + what's practice-changing).
- Authors, affiliations, ORCIDs, corresponding author; CRediT/contributions.
- Completed reporting checklist (CONSORT/STROBE/PRISMA).
- Disclosure forms; data-sharing statement; funding statement.
Final integrity sweep
- No over-claiming beyond the evidence (re-read abstract Conclusions and Discussion).
- Causal language only where the design supports it (cautious for observational).
- Registration number, denominators, and primary-outcome numbers consistent across abstract, text, tables, and flow diagram.
- Single-blind convention assumed unless instructed otherwise (confirm).
Templates
templates/checklist.md— copyable clinical preflight checklist.templates/cover_letter_template.md— clinical cover-letter scaffold.
Submission readiness pass for New England Journal of Medicine
Use this as a second-pass capability check. First lock the clinical question, population, endpoint, effect size, safety signal, and practice implication; then test whether the manuscript addresses clinical-medicine reviewers who expect practice-changing evidence, patient relevance, safety, and exact reporting discipline.
- Primary move: Verify portal, article type, anonymity, declarations, files, data/code, and current source-map facts; return blockers before formatting advice.
- Decision ledger: return
claim / evidence / blocker / next editrows so the next pass can patch the manuscript directly. - Neighbor test: compare against JAMA for broad clinical medicine, Lancet for global-health/public-health reach, specialty journals for narrower disease domains; if the neighboring outlet has the stronger audience claim, recommend re-routing before polishing.
- Verification floor: before submission-ready advice, re-open
resources/official-source-map.mdfor volatile rules and name the one unresolved fact that could change the recommendation.
Output format
【Blocking gaps】 [...] (must fix before upload — e.g., unregistered trial, missing CONSORT diagram)
【Warnings】 [...] (should fix)
【Files ready】 main / figures+tables / CONSORT diagram / protocol+SAP / cover letter / disclosures / data-sharing
【Verdict】 GO / NO-GO + the top 3 fixes
【Next】 submit | nejm-rebuttal (after decision)
Anti-patterns
- Do not upload a trial that was never prospectively registered without flagging it as a blocker.
- Do not submit an RCT without the CONSORT flow diagram and completed checklist.
- Do not omit the data-sharing statement or the role-of-the-funding-source statement.
- Do not rely on memory; run the checklist top to bottom.
Version History
- 1839142 Current 2026-07-05 14:06
