Agent Skills
› companion-inc/feynman
› esmfold2
esmfold2
GitHub用于快速预测蛋白质结构的技能，支持无MSA折叠、序列分选、变异结构筛查及置信度审查。
触发场景
需要快速蛋白质折叠假设
序列分选任务
变异结构筛查
结构置信度审查
安装
npx skills add companion-inc/feynman --skill esmfold2 -g -y
SKILL.md
Frontmatter
{
"name": "esmfold2",
"description": "Predict quick protein structures with ESMFold-style workflows. Use when a task needs fast MSA-free folding, sequence triage, variant structure screening, or confidence review."
}
ESMFold2
Use this skill when a fast protein fold hypothesis is useful before heavier structure prediction.
Workflow:
- Normalize sequences into FASTA and record identifiers, mutations, truncations, domains, and oligomer assumptions.
- Verify the local or endpoint route before running.
- Save FASTA, model version, command or request body, predicted PDB/mmCIF, pLDDT/confidence outputs, and logs.
- Flag low-confidence regions, missing multimers, disorder, membrane regions, and sequence lengths outside the chosen route's limits.
- Use RDKit/3Dmol/PDB previews and source-backed comparisons when the output influences a research decision.
Use ESMFold-style predictions for triage unless an independent check supports the structural claim.
版本历史
- 54d08a3 当前 2026-07-25 07:15
