Agent Skills › companion-inc/feynman › indication-dossier

indication-dossier

GitHub

用于构建生物医学适应症档案，整合疾病生物学、靶点依据、患者分层及临床试验等多源证据。

skills/indication-dossier/SKILL.md companion-inc/feynman

触发场景

需要汇总疾病生物学机制或靶点合理性分析要求提供患者细分、生物标志物或竞争性药物格局请求整理临床试验数据与转化医学证据

安装

npx skills add companion-inc/feynman --skill indication-dossier -g -y

更多选项

不安装直接使用

npx skills use companion-inc/feynman@indication-dossier

指定 Agent (Claude Code)

npx skills add companion-inc/feynman --skill indication-dossier -a claude-code -g -y

安装 repo 全部 skill

npx skills add companion-inc/feynman --all -g -y

预览 repo 内 skill

npx skills add companion-inc/feynman --list

SKILL.md

Frontmatter

{
    "name": "indication-dossier",
    "description": "Build a source-backed biomedical indication dossier. Use when a research task asks for disease biology, target rationale, patient segmentation, biomarkers, trials, drugs, competitive landscape, or translational evidence."
}

Indication Dossier

Use this skill to assemble a biomedical evidence packet for a disease, target, mechanism, biomarker, or therapy.

Workflow:

Define the indication, patient segment, intervention or target, and decision the dossier must support.
Gather evidence from literature, clinical trials, Open Targets, ChEMBL, CIViC, ClinGen, cBioPortal, DepMap/COSMIC-compatible sources, and other Feynman Bio Tools as relevant.
Separate human evidence, model-system evidence, mechanism, biomarkers, clinical precedent, safety, and open questions.
Rank claims by source strength and reproducibility. Flag missing cohorts, confounders, and assay limitations.
Save the dossier and provenance sidecar in outputs/.

Do not turn sparse evidence into a clinical recommendation.