Agent Skills › advaitpaliwal/feynman › indication-dossier

indication-dossier

GitHub

用于构建生物医学适应症的证据档案，整合疾病生物学、靶点理由、患者分层、生物标志物及临床试验等多源数据，支持药物研发决策。

skills/indication-dossier/SKILL.md advaitpaliwal/feynman

Trigger Scenarios

需要汇编特定疾病或靶点的生物医学证据包涉及患者分层、生物标志物或竞争格局的研究任务

Install

npx skills add advaitpaliwal/feynman --skill indication-dossier -g -y

More Options

Use without installing

npx skills use advaitpaliwal/feynman@indication-dossier

指定 Agent (Claude Code)

npx skills add advaitpaliwal/feynman --skill indication-dossier -a claude-code -g -y

安装 repo 全部 skill

npx skills add advaitpaliwal/feynman --all -g -y

预览 repo 内 skill

npx skills add advaitpaliwal/feynman --list

SKILL.md

Frontmatter

{
    "name": "indication-dossier",
    "description": "Build a source-backed biomedical indication dossier. Use when a research task asks for disease biology, target rationale, patient segmentation, biomarkers, trials, drugs, competitive landscape, or translational evidence."
}

Indication Dossier

Use this skill to assemble a biomedical evidence packet for a disease, target, mechanism, biomarker, or therapy.

Workflow:

Define the indication, patient segment, intervention or target, and decision the dossier must support.
Gather evidence from literature, clinical trials, Open Targets, ChEMBL, CIViC, ClinGen, cBioPortal, DepMap/COSMIC-compatible sources, and other Feynman Bio Tools as relevant.
Separate human evidence, model-system evidence, mechanism, biomarkers, clinical precedent, safety, and open questions.
Rank claims by source strength and reproducibility. Flag missing cohorts, confounders, and assay limitations.
Save the dossier and provenance sidecar in outputs/.

Do not turn sparse evidence into a clinical recommendation.