Agent Skillsaiming-lab/AutoResearchClaw › hypothesis-formulation

hypothesis-formulation

GitHub

指导从观察中结构化生成可验证科学假设,包括设定零/备择假设、提出竞争性解释及设计实验预测。适用于需要严谨实验设计和假设检验的研究场景。

researchclaw/skills/builtin/experiment/hypothesis-formulation/SKILL.md aiming-lab/AutoResearchClaw

触发场景

制定可验证的科学假设 设计对照实验以区分竞争性解释 进行假设检验与实验规划

安装

npx skills add aiming-lab/AutoResearchClaw --skill hypothesis-formulation -g -y
更多选项

非标准路径

npx skills add https://github.com/aiming-lab/AutoResearchClaw/tree/main/researchclaw/skills/builtin/experiment/hypothesis-formulation -g -y

不安装直接使用

npx skills use aiming-lab/AutoResearchClaw@hypothesis-formulation

指定 Agent (Claude Code)

npx skills add aiming-lab/AutoResearchClaw --skill hypothesis-formulation -a claude-code -g -y

安装 repo 全部 skill

npx skills add aiming-lab/AutoResearchClaw --all -g -y

预览 repo 内 skill

npx skills add aiming-lab/AutoResearchClaw --list

SKILL.md

Frontmatter
{
    "name": "hypothesis-formulation",
    "metadata": {
        "author": "researchclaw",
        "version": "1.0",
        "category": "experiment",
        "priority": "3",
        "references": "adapted from K-Dense-AI\/claude-scientific-skills",
        "trigger-keywords": "hypothesis,prediction,mechanism,falsifiable,null,alternative,testable",
        "applicable-stages": "7,8,9"
    },
    "description": "Structured scientific hypothesis generation from observations. Use when formulating testable hypotheses, competing explanations, or experimental predictions."
}

Hypothesis Formulation Best Practice

Structured Hypothesis Development

  1. Start with a clear observation or pattern that requires explanation
  2. Review existing literature for known mechanisms and prior explanations
  3. Identify what is already established vs. what remains uncertain
  4. Formulate the hypothesis as a specific, testable statement
  5. Ensure the hypothesis is falsifiable — define what outcome would refute it

Hypothesis Format

  1. Null hypothesis (H0): There is no effect or no difference
  2. Alternative hypothesis (H1): There is a specific, directional effect
  3. State both explicitly; design experiments to reject H0
  4. Use "If... then... because..." structure for mechanistic hypotheses:
    • If [independent variable is manipulated], then [predicted outcome], because [proposed mechanism]

Generating Competing Hypotheses

  1. Propose at least 2-3 plausible explanations for the same observation
  2. For each, identify unique predictions that distinguish it from alternatives
  3. Rank hypotheses by parsimony, consistency with prior evidence, and testability
  4. Design experiments that can discriminate between competing hypotheses
  5. Consider confounding variables that could produce the same observation

Testable Predictions

  1. Derive specific, measurable predictions from each hypothesis
  2. Define expected effect direction AND approximate magnitude
  3. Specify what experimental conditions would confirm vs. refute the prediction
  4. Identify potential confounds and plan controls to address them
  5. Ensure predictions are achievable with available methods and resources

Aligning with Experimental Design

  1. Map each hypothesis to a concrete experimental condition or comparison
  2. Ensure sample size is adequate to detect the predicted effect (power analysis)
  3. Pre-register hypotheses and analysis plans when possible
  4. Distinguish confirmatory (hypothesis-testing) from exploratory analyses
  5. Plan for both positive and null results — what will you conclude in each case?

版本历史

  • e2e23c9 当前 2026-07-25 07:48

同 Skill 集合

.claude/skills/a-evolve/SKILL.md
.claude/skills/biology-biopython/SKILL.md
.claude/skills/chemistry-rdkit/SKILL.md
.claude/skills/hypothesis-formulation/SKILL.md
.claude/skills/literature-search/SKILL.md
.claude/skills/researchclaw/SKILL.md
.claude/skills/scientific-visualization/SKILL.md
.claude/skills/scientific-writing/SKILL.md
.claude/skills/statistical-reporting/SKILL.md
external/agents/Biology-Agent/skills/fba-simulator/SKILL.md
external/agents/Biology-Agent/skills/flux-analyzer/SKILL.md
external/agents/Biology-Agent/skills/gsmm-builder/SKILL.md
external/agents/Biology-Agent/skills/gsmm-validator/SKILL.md
external/agents/Biology-Agent/skills/metabolic-study-planner/SKILL.md
external/agents/Biology-Agent/skills/mfa-pipeline-orchestrator/SKILL.md
external/agents/stat_research_agent/skills/stat-research-orchestrator/SKILL.md
external/agents/stat_research_agent/skills/stat-result-validator/SKILL.md
external/agents/stat_research_agent/skills/statistical-experimental-evaluation/SKILL.md
external/agents/stat_research_agent/skills/statistical-method-design/SKILL.md
external/agents/stat_research_agent/skills/statistical-problem-formulation/SKILL.md
external/agents/stat_research_agent/skills/statistical-theory-analysis/SKILL.md
researchclaw/skills/builtin/domain/biology-biopython/SKILL.md
researchclaw/skills/builtin/domain/chemistry-rdkit/SKILL.md
researchclaw/skills/builtin/domain/cv-classification/SKILL.md
researchclaw/skills/builtin/domain/cv-detection/SKILL.md
researchclaw/skills/builtin/domain/nlp-alignment/SKILL.md
researchclaw/skills/builtin/domain/nlp-pretraining/SKILL.md
researchclaw/skills/builtin/domain/quantum-qiskit/SKILL.md
researchclaw/skills/builtin/domain/rl-policy-optimization/SKILL.md
researchclaw/skills/builtin/experiment/experimental-design/SKILL.md
researchclaw/skills/builtin/experiment/literature-search/SKILL.md
researchclaw/skills/builtin/experiment/meta-analysis/SKILL.md
researchclaw/skills/builtin/experiment/scientific-visualization/SKILL.md
researchclaw/skills/builtin/experiment/scientific-writing/SKILL.md
researchclaw/skills/builtin/experiment/statistical-reporting/SKILL.md
researchclaw/skills/builtin/experiment/systematic-review/SKILL.md
researchclaw/skills/builtin/tooling/data-loading/SKILL.md
researchclaw/skills/builtin/tooling/distributed-training/SKILL.md
researchclaw/skills/builtin/tooling/mixed-precision/SKILL.md
researchclaw/skills/builtin/tooling/pytorch-training/SKILL.md

元信息

文件数
0
版本
be4ba47
Hash
9f8f83a8
收录时间
2026-07-25 07:48

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