Agent Skills › companion-inc/feynman › indication-dossier

indication-dossier

GitHub

用于构建生物医学适应症档案，整合疾病生物学、靶点依据、患者分层及临床试验等证据。

skills/indication-dossier/SKILL.md companion-inc/feynman

Trigger Scenarios

询问疾病生物学机制需要靶点合理性分析请求患者分层或生物标志物信息查询临床试验与竞争格局

Install

npx skills add companion-inc/feynman --skill indication-dossier -g -y

More Options

Use without installing

npx skills use companion-inc/feynman@indication-dossier

指定 Agent (Claude Code)

npx skills add companion-inc/feynman --skill indication-dossier -a claude-code -g -y

安装 repo 全部 skill

npx skills add companion-inc/feynman --all -g -y

预览 repo 内 skill

npx skills add companion-inc/feynman --list

SKILL.md

Frontmatter

{
    "name": "indication-dossier",
    "description": "Build a source-backed biomedical indication dossier. Use when a research task asks for disease biology, target rationale, patient segmentation, biomarkers, trials, drugs, competitive landscape, or translational evidence."
}

Indication Dossier

Use this skill to assemble a biomedical evidence packet for a disease, target, mechanism, biomarker, or therapy.

Workflow:

Define the indication, patient segment, intervention or target, and decision the dossier must support.
Gather evidence from literature, clinical trials, Open Targets, ChEMBL, CIViC, ClinGen, cBioPortal, DepMap/COSMIC-compatible sources, and other Feynman Bio Tools as relevant.
Separate human evidence, model-system evidence, mechanism, biomarkers, clinical precedent, safety, and open questions.
Rank claims by source strength and reproducibility. Flag missing cohorts, confounders, and assay limitations.
Save the dossier and provenance sidecar in outputs/.

Do not turn sparse evidence into a clinical recommendation.